B-type natriureticpeptide: circ effects
Pretest
Question 1
True or False
The human brain natriureticpeptide effects in patients with severe congestive heart failure include:
1. increased cardiac index
2. decreased mean pulmonary capillary wedge pressure.
3. decreased mean right atrial pressure.
4. decreased mean arterial pressure.
The pharmacological effects of infusion of human brain natriureticpeptide (hBNP) in patients with severe congestive heart failure were tested.
At the highest completed dose of the human brain natriureticpeptide, mean pulmonary artery pressure decreased; mean pulmonary capillary wedge pressure decreased; mean right atrial pressure decreased; mean arterial pressure decreased; and cardiac index
increased.
Urine volume and urine sodium excretion increased significantly during human brain natriureticpeptide infusion when compared with placebo infusion whereas creatinine clearance and urinary potassium excretion
did not change.
Infusion of incremental doses of human brain natriureticpeptide is associated with favorable hemodynamic and natriuretic effects in patients with severe congestive heart failure.
Postest
Question 1
True or False
The human brain natriuretic peptide effects in
patients with severe congestive heart failure include:
1. increased cardiac index
2. decreased mean pulmonary capillary wedge pressure.
3. decreased mean right atrial pressure.
4. decreased mean arterial pressure.
Answer:
TTTT
(Circulation. 1996;94:3184-3189.)
http://www.circ.ahajournals.org/cgi/content/abstract/94/12/3184